Conophyllidine, CAS [[152406-44-5]] Preis auf Anfrage

Artikelnummer: TGM-T211997
Artikelname: Conophyllidine, CAS [[152406-44-5]] Preis auf Anfrage
Artikelnummer: TGM-T211997
Hersteller Artikelnummer: T211997
Alternativnummer: TGM-T211997-10MG,TGM-T211997-50MG
Hersteller: TargetMol
Kategorie: Biochemikalien
Conophyllidine is a bisindole alkaloid and functions as a selective inhibitor of M2 polarization. It inhibits histone acetylation by targeting the histone acetyltransferase domain of the P300/CBP proteins. The IC50 of Conophyllidine for IL-4-induced arginase inhibition is 0.31 µM. This compound effectively induces tumor-associated macrophages (TAMs) to shift from an anti-inflammatory to an inflammatory state, thereby enhancing the recruitment and function of cytotoxic CD8+ T cells in the tumor microenvironment. Conophyllidine is useful for studying tumor-associated macrophages.
Molekulargewicht: 778.89
CAS Nummer: [152406-44-5]
Formel: C44H50N4O9
Target-Kategorie: Histone Acetyltransferase|||Arginase
T211997