PROTAC sEH-degrader-3, CAS [[3093413-94-3]] Preis auf Anfrage

Produktübersicht

• Artikelname: PROTAC sEH-degrader-3, CAS [[3093413-94-3]] Preis auf Anfrage
• Artikelnummer: TGM-T212556
• Hersteller Artikelnummer: T212556
• Alternativnummer: TGM-T212556-10MG,TGM-T212556-50MG
• Hersteller: TargetMol
• Kategorie: Biochemikalien

Produktbeschreibung

PROTACsEH-degrader-3 (Compound 1a) is a targeted sEH PROTAC degrader that selectively degrades cytosolic sEH without affecting sEH in peroxisomes. It degrades sEH through a CRBN-dependent lysosomal pathway rather than the proteasomal pathway, with an IC50 of 0.8 nM for hsEH. Additionally, PROTACsEH-degrader-3 inhibits endoplasmic reticulum stress, making it useful for research on diseases related to inflammation, metabolic disorders, and other conditions associated with endoplasmic reticulum stress.

Produkteigenschaften

• Molekulargewicht: 970.94
• CAS Nummer: [3093413-94-3]
• Formel: C46H53F3N6O14
• Target-Kategorie: Epoxide Hydrolase|||PROTACs

Bilder

T212556