PROTAC sEH-degrader-3, CAS [[3093413-94-3]] Preis auf Anfrage
Biozol Catalog Number:
TGM-T212556
Supplier Catalog Number:
T212556
Alternative Catalog Number:
TGM-T212556-10MG,TGM-T212556-50MG
Manufacturer:
TargetMol
Category:
Biochemikalien
PROTACsEH-degrader-3 (Compound 1a) is a targeted sEH PROTAC degrader that selectively degrades cytosolic sEH without affecting sEH in peroxisomes. It degrades sEH through a CRBN-dependent lysosomal pathway rather than the proteasomal pathway, with an IC50 of 0.8 nM for hsEH. Additionally, PROTACsEH-degrader-3 inhibits endoplasmic reticulum stress, making it useful for research on diseases related to inflammation, metabolic disorders, and other conditions associated with endoplasmic reticulum stress.
Molecular Weight:
970.94
CAS Number:
[3093413-94-3]
Formula:
C46H53F3N6O14
Target:
Epoxide Hydrolase|||PROTACs
T212556
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