M6766, CAS [[696628-90-7]]

Produktübersicht

• Artikelname: M6766, CAS [[696628-90-7]]
• Artikelnummer: TGM-T212821
• Hersteller Artikelnummer: T212821
• Alternativnummer: TGM-T212821-1MG,TGM-T212821-5MG,TGM-T212821-10MG,TGM-T212821-25MG,TGM-T212821-50MG,TGM-T212821-100MG
• Hersteller: TargetMol
• Kategorie: Biochemikalien

Produktbeschreibung

M6766 is a selective and potent inhibitor of endoplasmic reticulum oxidoreductase 1alpha (ERO1alpha), exhibiting an IC50 of 1.4 uM and a KD of 1.1 uM. It also inhibits ERO1beta with an IC50 of 7.2 uM. M6766 exerts its inhibitory effect by binding to the flavin adenine dinucleotide (FAD)-binding pocket of ERO1alpha. Functionally, M6766 suppresses granule secretion, alphaIIbbeta3 integrin activation, Ca2+ mobilization, and platelet aggregation. It serves as a significant chemical probe for investigating the molecular pathways of arterial thrombosis and neurological disorders, such as ischemic stroke.

Produkteigenschaften

• Molekulargewicht: 360.44
• Reinheit: 99.17%
• CAS Nummer: [696628-90-7]
• Formel: C19H16N6S
• Target-Kategorie: Reactive Oxygen Species

Bilder

T212821