MSU-44147 is a small-molecule inhibitor that targets the membrane transport protein MmpL3 in Mycobacterium abscessus. MSU-44147 exhibits selective anti-mycobacterial activity and low cytotoxicity toward eukaryotic cells. By inhibiting MmpL3-mediated lipid transport, MSU-44147 disrupts cell wall synthesis and biofilm formation, and exhibits bactericidal activity against intracellular bacteria, simultaneously, it produces additive or synergistic effects when used in combination with various antibiotics.
Molekulargewicht:
313.36
Reinheit:
99.81%
CAS Nummer:
[3105177-29-2]
Formel:
C17H22F3NO
Target-Kategorie:
Antibacterial
T212840
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten