Hakin-1 is an inhibitor of the E3 ubiquitin ligase Hakai. It effectively blocks both overall ubiquitination mediated by Hakai and the specific ubiquitination of E-cadherin, thereby inhibiting the process of epithelial-mesenchymal transition (EMT). Hakin-1 can impede tumor progression and cancer metastasis and is utilized for research in colorectal cancer and other cancers.
Molekulargewicht:
385.35
CAS Nummer:
[346660-34-2]
Formel:
C16H11N5O5S
Target-Kategorie:
E1/E2/E3 Enzyme|||Cadherin
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten
