MBL-II-141, CAS [[1353747-12-2]] Preis auf Anfrage

Produktübersicht

• Artikelname: MBL-II-141, CAS [[1353747-12-2]] Preis auf Anfrage
• Artikelnummer: TGM-T213054
• Hersteller Artikelnummer: T213054
• Alternativnummer: TGM-T213054-10MG,TGM-T213054-50MG
• Hersteller: TargetMol
• Kategorie: Biochemikalien

Produktbeschreibung

MBL-II-141 is a potent ABCG2 inhibitor with an IC50 of 0.11 µM. It inhibits the transport function of ABCG2 in a non-competitive manner, preventing ABCG2 from expelling substrates (such as Irinotecan) out of cells, thereby increasing the intracellular accumulation of the drug. MBL-II-141 does not affect ABCB1 (P-gp) or ABCC1 (MRP1) and exhibits very low cytotoxicity (IG50 > 100 µM). This compound is useful for studying tumor multidrug resistance (MDR).

Produkteigenschaften

• Molekulargewicht: 547.41
• CAS Nummer: [1353747-12-2]
• Formel: C28H23BrN2O5
• Target-Kategorie: BCRP