MBL-II-141, CAS [[1353747-12-2]] Preis auf Anfrage

Product Overview

• Article Name: MBL-II-141, CAS [[1353747-12-2]] Preis auf Anfrage
• Biozol Catalog Number: TGM-T213054
• Supplier Catalog Number: T213054
• Alternative Catalog Number: TGM-T213054-10MG,TGM-T213054-50MG
• Manufacturer: TargetMol
• Category: Biochemikalien

Product Description

MBL-II-141 is a potent ABCG2 inhibitor with an IC50 of 0.11 µM. It inhibits the transport function of ABCG2 in a non-competitive manner, preventing ABCG2 from expelling substrates (such as Irinotecan) out of cells, thereby increasing the intracellular accumulation of the drug. MBL-II-141 does not affect ABCB1 (P-gp) or ABCC1 (MRP1) and exhibits very low cytotoxicity (IG50 > 100 µM). This compound is useful for studying tumor multidrug resistance (MDR).

Product Properties

• Molecular Weight: 547.41
• CAS Number: [1353747-12-2]
• Formula: C28H23BrN2O5
• Target: BCRP