UK122 hydrochloride is a potent and selective inhibitor of urokinase-type plasminogen activator (uPA), with an IC50 of 0.2 µM. It shows little to no inhibitory effect on tissue-type PA (tPA), plasmin, thrombin, and trypsin (IC50 > 100 µM for all). As a 4-oxazolidinone analog, UK122 hydrochloride acts as an anti-cancer agent by inhibiting cancer cell migration and invasion.
Molekulargewicht:
327.76
Formel:
C17H14ClN3O2
Target-Kategorie:
Serine Protease
T214657
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten
