UK122 hydrochloride is a potent and selective inhibitor of urokinase-type plasminogen activator (uPA), with an IC50 of 0.2 µM. It shows little to no inhibitory effect on tissue-type PA (tPA), plasmin, thrombin, and trypsin (IC50 > 100 µM for all). As a 4-oxazolidinone analog, UK122 hydrochloride acts as an anti-cancer agent by inhibiting cancer cell migration and invasion.
Molecular Weight:
327.76
Formula:
C17H14ClN3O2
Target:
Serine Protease
T214657
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