Plinabulin, CAS [[714272-27-2]]
Artikelnummer:
TGM-T2511
- Bilder (1)
| Artikelname: | Plinabulin, CAS [[714272-27-2]] |
| Artikelnummer: | TGM-T2511 |
| Hersteller Artikelnummer: | T2511 |
| Alternativnummer: | TGM-T2511-1MLX10MM(INDMSO),TGM-T2511-2MG,TGM-T2511-5MG,TGM-T2511-10MG,TGM-T2511-25MG,TGM-T2511-50MG,TGM-T2511-100MG |
| Hersteller: | TargetMol |
| Kategorie: | Biochemikalien |
| Alternative Synonym: | NPI-2358 |
| Plinabulin (NPI-2358) (NPI-2358) is a vascular disrupting agent (VDA) against tubulin-depolymerizing tumor cells ( IC50: 9.8-18 nM). Plinabulin selectively targets and binds to the colchicine-binding site of tubulin, thereby interrupting equilibrium of microtubule dynamics. This disrupts mitotic spindle assembly leading to cell cycle arrest at M phase and blockage of cell division. |
| Molekulargewicht: | 336.39 |
| Reinheit: | 91.68% |
| CAS Nummer: | [714272-27-2] |
| Formel: | C19H20N4O2 |
| Target-Kategorie: | Microtubule Associated |

