Ivabradine hydrochloride, CAS [[148849-67-6]]

Artikelnummer: TGM-T2535
Artikelname: Ivabradine hydrochloride, CAS [[148849-67-6]]
Artikelnummer: TGM-T2535
Hersteller Artikelnummer: T2535
Alternativnummer: TGM-T2535-1MLX10MM(INDMSO),TGM-T2535-10MG,TGM-T2535-25MG,TGM-T2535-50MG,TGM-T2535-100MG,TGM-T2535-200MG,TGM-T2535-500MG
Hersteller: TargetMol
Kategorie: Biochemikalien
Alternative Synonym: Ivabradine HCl , S 16257-2
Ivabradine hydrochloride (S 16257-2) is a new If inhibitor (IC50: 2.9 µM). Ivabradine Hydrochloride is the hydrochloride salt form of ivabradine, an orally bioavailable, hyperpolarization-activated, cyclic nucleotide-gated (HCN) channel blocker, with negative chronotropic activity. Upon administration, ivabradine selectively binds to the intracellular portion of the HCN channel pore and blocks HCN channels in the pacemaker cells within the sinoatrial (SA) node. This inhibits the If (funny) pacemaker ion current, prevents the inward flow and intracellular accumulation of positively charged ions, reduces pacemaker activity and slows diastolic depolarization.
Molekulargewicht: 505.05
Reinheit: 99.73%
CAS Nummer: [148849-67-6]
Formel: C27H37ClN2O5
Target-Kategorie: Adrenergic Receptor|||HCN Channel
T2535