Ivabradine hydrochloride, CAS [[148849-67-6]]

Product Overview

• Article Name: Ivabradine hydrochloride, CAS [[148849-67-6]]
• Biozol Catalog Number: TGM-T2535
• Supplier Catalog Number: T2535
• Alternative Catalog Number: TGM-T2535-1MLX10MM(INDMSO),TGM-T2535-10MG,TGM-T2535-25MG,TGM-T2535-50MG,TGM-T2535-100MG,TGM-T2535-200MG,TGM-T2535-500MG
• Manufacturer: TargetMol
• Category: Biochemikalien
• Alternative Names: Ivabradine HCl , S 16257-2

Product Description

Ivabradine hydrochloride (S 16257-2) is a new If inhibitor (IC50: 2.9 µM). Ivabradine Hydrochloride is the hydrochloride salt form of ivabradine, an orally bioavailable, hyperpolarization-activated, cyclic nucleotide-gated (HCN) channel blocker, with negative chronotropic activity. Upon administration, ivabradine selectively binds to the intracellular portion of the HCN channel pore and blocks HCN channels in the pacemaker cells within the sinoatrial (SA) node. This inhibits the If (funny) pacemaker ion current, prevents the inward flow and intracellular accumulation of positively charged ions, reduces pacemaker activity and slows diastolic depolarization.

Product Properties

• Molecular Weight: 505.05
• Purity: 99.73%
• CAS Number: [148849-67-6]
• Formula: C27H37ClN2O5
• Target: Adrenergic Receptor|||HCN Channel

Images

T2535