BMS 182874 is an orally effective and highly selective endothelin receptor ETA antagonist with an IC50 value of 0.150 µM for ETA and a Ki value of 0.055 µM for ETA.BMS 182874 is able to reduce arterial pressure in a rat hypertension model induced by Deoxycorticosterone acetate. BMS 182874 was able to reduce Deoxycorticosterone-induced arterial pressure in a rat model of hypertension and can be used to study cardiovascular disease.
Molekulargewicht:
345.42
Reinheit:
98.38%
CAS Nummer:
[153042-42-3]
Formel:
C17H19N3O3S
Target-Kategorie:
Endothelin Receptor
T26841
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten