GDC0575 monohydrochloride, CAS [[1196504-54-7]]

Produktübersicht

• Artikelname: GDC0575 monohydrochloride, CAS [[1196504-54-7]]
• Artikelnummer: TGM-T27407
• Hersteller Artikelnummer: T27407
• Alternativnummer: TGM-T27407-1MLX10MM(INDMSO),TGM-T27407-1MG,TGM-T27407-2MG,TGM-T27407-5MG,TGM-T27407-10MG,TGM-T27407-25MG,TGM-T27407-50MG,TGM-T27407-100MG,TGM-T27407-200MG
• Hersteller: TargetMol
• Kategorie: Biochemikalien
• Alternative Synonym: GDC 0575 , ARRY575 , GDC0575 , ARRY-575 , GDC-0575

Produktbeschreibung

GDC0575 monohydrochloride (ARRY575) is a potent and selective inhibitor of cell cycle checkpoint kinase 1 (Chk1) with an IC50 of 1.2 nM. GDC-0575 specifically binds to and inhibits Chk1, this may result in tumor cells bypassing Chk1-dependent cell cycle arrest in the S and G2/M phases, which permits the cells to undergo DNA repair prior to entry into mitosis.

Produkteigenschaften

• Molekulargewicht: 414.73
• Reinheit: 0.9785
• CAS Nummer: [1196504-54-7]
• Formel: C16H21BrClN5O
• Target-Kategorie: Chk

Bilder

T27407