COH29, CAS [[1190932-38-7]]

Produktübersicht

• Artikelname: COH29, CAS [[1190932-38-7]]
• Artikelnummer: TGM-T3157
• Hersteller Artikelnummer: T3157
• Alternativnummer: TGM-T3157-1MLX10MM(INDMSO),TGM-T3157-1MG,TGM-T3157-2MG,TGM-T3157-5MG,TGM-T3157-10MG,TGM-T3157-25MG,TGM-T3157-50MG,TGM-T3157-100MG,TGM-T3157-200MG
• Hersteller: TargetMol
• Kategorie: Biochemikalien
• Alternative Synonym: RNR Inhibitor COH29

Produktbeschreibung

COH29 (RNR Inhibitor COH29) is an orally available, aromatically substituted thiazole and human ribonucleotide reductase (RNR) inhibitor with potential antineoplastic activity. COH29 binds to the ligand-binding pocket of the RNR M2 subunit (hRRM2) near the C-terminal tail, decreasing the pool of deoxyribonucleotide triphosphates needed for DNA synthesis, leading to cell cycle arrest and growth inhibition. It may also inhibit the nuclear enzyme poly (ADP-ribose) polymerase (PARP) 1, preventing DNA repair, causing accumulation of DNA breaks, and inducing apoptosis.

Produkteigenschaften

• Molekulargewicht: 420.44
• Reinheit: 98.92%
• CAS Nummer: [1190932-38-7]
• Formel: C22H16N2O5S
• Target-Kategorie: DNA/RNA Synthesis

Bilder

T3157