Setipiprant, CAS [[866460-33-5]]
Artikelnummer:
TGM-T3520
- Bilder (1)
| Artikelname: | Setipiprant, CAS [[866460-33-5]] |
| Artikelnummer: | TGM-T3520 |
| Hersteller Artikelnummer: | T3520 |
| Alternativnummer: | TGM-T3520-1MLX10MM(INDMSO),TGM-T3520-10MG,TGM-T3520-25MG,TGM-T3520-50MG,TGM-T3520-100MG,TGM-T3520-200MG |
| Hersteller: | TargetMol |
| Kategorie: | Biochemikalien |
| Alternative Synonym: | KYTH-105 , ACT-129968 |
| Setipiprant (ACT-129968) is an orally available, selective CRTH2 antagonist (IC50: 6.0 nM). CRTH2, a G protein-coupled receptor for prostaglandin (PGD2), mediates key inflammatory responses related to allergy and asthma. PGD2, produced by mast cells, binds to CRTH2 on blood-borne cells, inducing chemotaxis of Th2 cells, basophils, and eosinophils, and stimulating cytokine release. |
| Molekulargewicht: | 402.42 |
| Reinheit: | 99.16% |
| CAS Nummer: | [866460-33-5] |
| Formel: | C24H19FN2O3 |
| Target-Kategorie: | Prostaglandin Receptor|||GPCR |

