Setipiprant, CAS [[866460-33-5]]

Product Overview

• Article Name: Setipiprant, CAS [[866460-33-5]]
• Biozol Catalog Number: TGM-T3520
• Supplier Catalog Number: T3520
• Alternative Catalog Number: TGM-T3520-1MLX10MM(INDMSO),TGM-T3520-10MG,TGM-T3520-25MG,TGM-T3520-50MG,TGM-T3520-100MG,TGM-T3520-200MG
• Manufacturer: TargetMol
• Category: Biochemikalien
• Alternative Names: KYTH-105 , ACT-129968

Product Description

Setipiprant (ACT-129968) is an orally available, selective CRTH2 antagonist (IC50: 6.0 nM). CRTH2, a G protein-coupled receptor for prostaglandin (PGD2), mediates key inflammatory responses related to allergy and asthma. PGD2, produced by mast cells, binds to CRTH2 on blood-borne cells, inducing chemotaxis of Th2 cells, basophils, and eosinophils, and stimulating cytokine release.

Product Properties

• Molecular Weight: 402.42
• Purity: 99.16%
• CAS Number: [866460-33-5]
• Formula: C24H19FN2O3
• Target: Prostaglandin Receptor|||GPCR

Images

T3520