FD223, CAS [[2050524-24-6]]

Produktübersicht

• Artikelname: FD223, CAS [[2050524-24-6]]
• Artikelnummer: TGM-T35531
• Hersteller Artikelnummer: T35531
• Alternativnummer: TGM-T35531-25MG,TGM-T35531-50MG,TGM-T35531-100MG
• Hersteller: TargetMol
• Kategorie: Biochemikalien

Produktbeschreibung

FD223 is a potent, selective phosphoinositide 3-kinase delta (PI3Kdelta) inhibitor with a marked affinity (IC50=1 nM), demonstrating notable selectivity against other isoforms (IC50s: alpha=51 nM, beta=29 nM, gamma=37 nM). This compound effectively suppresses the proliferation of acute myeloid leukemia (AML) cell lines by inhibiting p-AKT Ser473, thereby inducing G1 phase cell cycle arrest. FD223 holds promise for leukemia research, particularly in AML[1].

Produkteigenschaften

• Molekulargewicht: 385.83
• CAS Nummer: [2050524-24-6]
• Formel: C17H12ClN5O2S
• Target-Kategorie: Others|||PI3K|||Apoptosis

Bilder

T35531