FD223, CAS [[2050524-24-6]]
Catalog Number:
TGM-T35531
| Article Name: |
FD223, CAS [[2050524-24-6]] |
| Biozol Catalog Number: |
TGM-T35531 |
| Supplier Catalog Number: |
T35531 |
| Alternative Catalog Number: |
TGM-T35531-25MG,TGM-T35531-50MG,TGM-T35531-100MG |
| Manufacturer: |
TargetMol |
| Category: |
Biochemikalien |
| FD223 is a potent, selective phosphoinositide 3-kinase delta (PI3Kdelta) inhibitor with a marked affinity (IC50=1 nM), demonstrating notable selectivity against other isoforms (IC50s: alpha=51 nM, beta=29 nM, gamma=37 nM). This compound effectively suppresses the proliferation of acute myeloid leukemia (AML) cell lines by inhibiting p-AKT Ser473, thereby inducing G1 phase cell cycle arrest. FD223 holds promise for leukemia research, particularly in AML[1]. |
| Molecular Weight: |
385.83 |
| CAS Number: |
[2050524-24-6] |
| Formula: |
C17H12ClN5O2S |
| Target: |
Others|||PI3K|||Apoptosis |
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|
T35531 |
