Ganglioside GD3 Mixture (sodium salt), CAS [[62010-37-1]]

Produktübersicht

• Artikelname: Ganglioside GD3 Mixture (sodium salt), CAS [[62010-37-1]]
• Artikelnummer: TGM-T35552
• Hersteller Artikelnummer: T35552
• Alternativnummer: TGM-T35552-25MG
• Hersteller: TargetMol
• Kategorie: Biochemikalien

Produktbeschreibung

Ganglioside GD3 is synthesized by the addition of two sialic acid residues to lactosylceramide and can serve as a precursor to the formation of more complex gangliosides by the action of glycosyl- and sialyltransferases. It induces apoptosis in HuT-78 cutaneous T cell lymphoma cells in a concentration-dependent manner and disrupts the mitochondrial membrane potential when used at a concentration of 200 µM. Expression of ganglioside GD3 in GD3-negative SK-MEL-28-N1 malignant melanoma cells increases both cell proliferation and invasion in vitro. Ganglioside GD3-deficient adult mice exhibit progressive loss of the neural stem cell (NSC) pool and impaired neurogenesis. Ganglioside GD3 mixture contains ganglioside GD3 molecular species with C18:1 and C20:1 sphingoid backbones.

Produkteigenschaften

• Molekulargewicht: 1516.726
• CAS Nummer: [62010-37-1]
• Formel: C70H123N3Na2O29
• Target-Kategorie: Others

Bilder

T35552