Ganglioside GD3 Mixture (sodium salt), CAS [[62010-37-1]]

Product Overview

• Article Name: Ganglioside GD3 Mixture (sodium salt), CAS [[62010-37-1]]
• Biozol Catalog Number: TGM-T35552
• Supplier Catalog Number: T35552
• Alternative Catalog Number: TGM-T35552-25MG
• Manufacturer: TargetMol
• Category: Biochemikalien

Product Description

Ganglioside GD3 is synthesized by the addition of two sialic acid residues to lactosylceramide and can serve as a precursor to the formation of more complex gangliosides by the action of glycosyl- and sialyltransferases. It induces apoptosis in HuT-78 cutaneous T cell lymphoma cells in a concentration-dependent manner and disrupts the mitochondrial membrane potential when used at a concentration of 200 µM. Expression of ganglioside GD3 in GD3-negative SK-MEL-28-N1 malignant melanoma cells increases both cell proliferation and invasion in vitro. Ganglioside GD3-deficient adult mice exhibit progressive loss of the neural stem cell (NSC) pool and impaired neurogenesis. Ganglioside GD3 mixture contains ganglioside GD3 molecular species with C18:1 and C20:1 sphingoid backbones.

Product Properties

• Molecular Weight: 1516.726
• CAS Number: [62010-37-1]
• Formula: C70H123N3Na2O29
• Target: Others

Images

T35552