Cylindrospermopsin, CAS [[143545-90-8]] Preis auf Anfrage

Produktübersicht

• Artikelname: Cylindrospermopsin, CAS [[143545-90-8]] Preis auf Anfrage
• Artikelnummer: TGM-T35770
• Hersteller Artikelnummer: T35770
• Alternativnummer: TGM-T35770-50UG,TGM-T35770-100UG
• Hersteller: TargetMol
• Kategorie: Biochemikalien

Produktbeschreibung

Cylindrospermopsin, a tricyclic uracil derivative, is a cyanobacterial toxin that was first discovered in an algal bloom contaminating a local drinking supply on Palm Island in Queensland, Australia after an outbreak of a mysterious disease. Cylindrospermopsin targets protein and glutathione synthesis in hepatocytes (IC50s = 1.3 and 2.4 &181M, respectively), leading to cell death. [1] It has been shown to inhibit the activity of the uridine monophosphate synthase complex with a Ki value of 10 &181M.[2] Cylindrospermopsin is genotoxic, inducing DNA damage as evidenced by double strand breaks and reducing cell viability in HepG2 cells at 0.1-0.5 &181g/ml.[3]

Produkteigenschaften

• Molekulargewicht: 415.42
• CAS Nummer: [143545-90-8]
• Formel: C15H21N5O7S
• Target-Kategorie: DNA/RNA Synthesis|||Others

Bilder

T35770