Cylindrospermopsin, CAS [[143545-90-8]] Preis auf Anfrage
Biozol Catalog Number:
TGM-T35770
Supplier Catalog Number:
T35770
Alternative Catalog Number:
TGM-T35770-50UG,TGM-T35770-100UG
Manufacturer:
TargetMol
Category:
Biochemikalien
Cylindrospermopsin, a tricyclic uracil derivative, is a cyanobacterial toxin that was first discovered in an algal bloom contaminating a local drinking supply on Palm Island in Queensland, Australia after an outbreak of a mysterious disease. Cylindrospermopsin targets protein and glutathione synthesis in hepatocytes (IC50s = 1.3 and 2.4 &181M, respectively), leading to cell death. [1] It has been shown to inhibit the activity of the uridine monophosphate synthase complex with a Ki value of 10 &181M.[2] Cylindrospermopsin is genotoxic, inducing DNA damage as evidenced by double strand breaks and reducing cell viability in HepG2 cells at 0.1-0.5 &181g/ml.[3]
Molecular Weight:
415.42
CAS Number:
[143545-90-8]
Formula:
C15H21N5O7S
Target:
DNA/RNA Synthesis|||Others
T35770
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