AZD 1152 (hydrochloride), CAS [[722543-50-2]]

Produktübersicht

• Artikelname: AZD 1152 (hydrochloride), CAS [[722543-50-2]]
• Artikelnummer: TGM-T36199
• Hersteller Artikelnummer: T36199
• Alternativnummer: TGM-T36199-1MG,TGM-T36199-5MG,TGM-T36199-10MG,TGM-T36199-25MG
• Hersteller: TargetMol
• Kategorie: Biochemikalien

Produktbeschreibung

AZD 1152 is an orally bioavailable prodrug of AZD 1152-HQPA, a selective inhibitor of Aurora kinase B (IC50= 0.36 nM).1AZD 1152 is converted to AZD 1152-HQPA in plasma. Inhibition of Aurora B results in disruption of spindle checkpoint functions and chromosome alignment, resulting in inhibition of cytokinesis followed by apoptosis.2,3AZD 1152 inhibits tumor xenograft growthin vivo.4,5

Produkteigenschaften

• Molekulargewicht: 660.47
• CAS Nummer: [722543-50-2]
• Formel: C26H33Cl2FN7O6P
• Target-Kategorie: Others|||Aurora Kinase|||Apoptosis

Bilder

T36199