SJF 8240, CAS [[2230821-68-6]]

Produktübersicht

• Artikelname: SJF 8240, CAS [[2230821-68-6]]
• Artikelnummer: TGM-T36246
• Hersteller Artikelnummer: T36246
• Alternativnummer: TGM-T36246-5MG
• Hersteller: TargetMol
• Kategorie: Biochemikalien

Produktbeschreibung

c-MET degrader. Comprises MET inhibitor foretinib (GSK 1363089) joined by a linker to a von Hippel-Lindau (VHL) recruiting ligand. Degrades c-MET within 6 hours in vitro. Inhibits agonist-driven AKT phosphorylation and GTL16 cell proliferation (IC50 = 66.7 nM). Also degrades exon-14-deleted c-MET in Hs746T cells.

Produkteigenschaften

• Molekulargewicht: 1106.25
• CAS Nummer: [2230821-68-6]
• Formel: C58H65F2N7O11S
• Target-Kategorie: Others|||c-Met/HGFR|||PROTACs

Bilder

T36246