SJF 8240, CAS [[2230821-68-6]]

Product Overview

• Article Name: SJF 8240, CAS [[2230821-68-6]]
• Biozol Catalog Number: TGM-T36246
• Supplier Catalog Number: T36246
• Alternative Catalog Number: TGM-T36246-5MG
• Manufacturer: TargetMol
• Category: Biochemikalien

Product Description

c-MET degrader. Comprises MET inhibitor foretinib (GSK 1363089) joined by a linker to a von Hippel-Lindau (VHL) recruiting ligand. Degrades c-MET within 6 hours in vitro. Inhibits agonist-driven AKT phosphorylation and GTL16 cell proliferation (IC50 = 66.7 nM). Also degrades exon-14-deleted c-MET in Hs746T cells.

Product Properties

• Molecular Weight: 1106.25
• CAS Number: [2230821-68-6]
• Formula: C58H65F2N7O11S
• Target: Others|||c-Met/HGFR|||PROTACs

Images

T36246