Crenigacestat, CAS [[1421438-81-4]]
Artikelnummer:
TGM-T3633
- Bilder (1)
| Artikelname: | Crenigacestat, CAS [[1421438-81-4]] |
| Artikelnummer: | TGM-T3633 |
| Hersteller Artikelnummer: | T3633 |
| Alternativnummer: | TGM-T3633-1MLX10MM(INDMSO),TGM-T3633-1MG,TGM-T3633-5MG,TGM-T3633-10MG,TGM-T3633-25MG,TGM-T3633-50MG |
| Hersteller: | TargetMol |
| Kategorie: | Biochemikalien |
| Alternative Synonym: | LY3039478 |
| Crenigacestat (LY3039478) is an orally bioavailable Notch inhibitor with an IC50 of ~1 nM in most tumor cell lines tested. It effectively inhibits mutant Notch receptor activity and, in a xenograft tumor model, inhibits the expression of Notch-regulated genes and N1ICD cleavage in the tumor microenvironment. |
| Molekulargewicht: | 464.44 |
| Reinheit: | 97.27% |
| CAS Nummer: | [1421438-81-4] |
| Formel: | C22H23F3N4O4 |
| Target-Kategorie: | Gamma-secretase |

