Crenigacestat, CAS [[1421438-81-4]]

Product Overview

• Article Name: Crenigacestat, CAS [[1421438-81-4]]
• Biozol Catalog Number: TGM-T3633
• Supplier Catalog Number: T3633
• Alternative Catalog Number: TGM-T3633-1MLX10MM(INDMSO),TGM-T3633-1MG,TGM-T3633-5MG,TGM-T3633-10MG,TGM-T3633-25MG,TGM-T3633-50MG
• Manufacturer: TargetMol
• Category: Biochemikalien
• Alternative Names: LY3039478

Product Description

Crenigacestat (LY3039478) is an orally bioavailable Notch inhibitor with an IC50 of ~1 nM in most tumor cell lines tested. It effectively inhibits mutant Notch receptor activity and, in a xenograft tumor model, inhibits the expression of Notch-regulated genes and N1ICD cleavage in the tumor microenvironment.

Product Properties

• Molecular Weight: 464.44
• Purity: 97.27%
• CAS Number: [1421438-81-4]
• Formula: C22H23F3N4O4
• Target: Gamma-secretase

Images

T3633