Pifithrin-beta hydrobromide, CAS [[511296-88-1]]
Artikelnummer:
TGM-T3637
- Bilder (1)
| Artikelname: | Pifithrin-beta hydrobromide, CAS [[511296-88-1]] |
| Artikelnummer: | TGM-T3637 |
| Hersteller Artikelnummer: | T3637 |
| Alternativnummer: | TGM-T3637-1MLX10MM(INDMSO),TGM-T3637-2MG,TGM-T3637-5MG,TGM-T3637-10MG,TGM-T3637-25MG,TGM-T3637-50MG,TGM-T3637-100MG |
| Hersteller: | TargetMol |
| Kategorie: | Biochemikalien |
| Alternative Synonym: | Cyclic Pifithrin-alpha hydrobromide , Cyclic PFT-alpha , Pifithrin-beta , PFT-beta , PFT beta (hydrobromide) |
| Pifithrin-beta hydrobromide (Cyclic PFT-alpha) is an inhibitor of p53, reversibly blocks p53-dependent transcriptional activation and apoptosis. Protects against neuronal death in models of stroke and neurodegenerative disorders. Active in vivo, protects mice from the side-effects of Y therapy associated with p53 induction. Supresses self-renewal of embryonic stem cells. Also aryl hydrocarbon receptor (AHR) agonist, causes upregulation of AHR target gene CYP1A1 (EC50 = 1.1 µM). |
| Molekulargewicht: | 349.29 |
| Reinheit: | 99.24% |
| CAS Nummer: | [511296-88-1] |
| Formel: | C16H17BrN2S |
| Target-Kategorie: | p53|||MDM-2/p53|||Ferroptosis |

