Pifithrin-beta hydrobromide, CAS [[511296-88-1]]

Product Overview

• Article Name: Pifithrin-beta hydrobromide, CAS [[511296-88-1]]
• Biozol Catalog Number: TGM-T3637
• Supplier Catalog Number: T3637
• Alternative Catalog Number: TGM-T3637-1MLX10MM(INDMSO),TGM-T3637-2MG,TGM-T3637-5MG,TGM-T3637-10MG,TGM-T3637-25MG,TGM-T3637-50MG,TGM-T3637-100MG
• Manufacturer: TargetMol
• Category: Biochemikalien
• Alternative Names: Cyclic Pifithrin-alpha hydrobromide , Cyclic PFT-alpha , Pifithrin-beta , PFT-beta , PFT beta (hydrobromide)

Product Description

Pifithrin-beta hydrobromide (Cyclic PFT-alpha) is an inhibitor of p53, reversibly blocks p53-dependent transcriptional activation and apoptosis. Protects against neuronal death in models of stroke and neurodegenerative disorders. Active in vivo, protects mice from the side-effects of Y therapy associated with p53 induction. Supresses self-renewal of embryonic stem cells. Also aryl hydrocarbon receptor (AHR) agonist, causes upregulation of AHR target gene CYP1A1 (EC50 = 1.1 µM).

Product Properties

• Molecular Weight: 349.29
• Purity: 99.24%
• CAS Number: [511296-88-1]
• Formula: C16H17BrN2S
• Target: p53|||MDM-2/p53|||Ferroptosis

Images

T3637