Nocardamine is a ferrioxamine siderophore that has been found inStreptomycesand has diverse biological activities.1,2,3,4It chelates iron in a chrome azurol S assay (IC50= 9.9 µM).1Nocardamine inhibitsM. smegmatisandM. bovisbiofilm formation (MIC = 10 µM for both), an effect that can be reversed by iron.2It is cytotoxic to T47D, SK-MEL-5, SK-MEL-28, and RPMI-7951 cancer cells (IC50s = 6, 18, 12, and 14 µM, respectively).3Nocardamine also induces morphological changes in BM-N4 insect cells.4
Molekulargewicht:
600.7
CAS Nummer:
[26605-16-3]
Formel:
C27H48N6O9
Target-Kategorie:
Others
T36539
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten