PROTAC IDO1 Degrader-1, CAS [[2488851-89-2]]

Produktübersicht

• Artikelname: PROTAC IDO1 Degrader-1, CAS [[2488851-89-2]]
• Artikelnummer: TGM-T37329
• Hersteller Artikelnummer: T37329
• Alternativnummer: TGM-T37329-5MG
• Hersteller: TargetMol
• Kategorie: Biochemikalien
• Alternative Synonym: PROTAC IDO1 Degrader-1

Produktbeschreibung

PROTAC IDO1 Degrader-1, a pioneering compound, efficiently targets indoleamine 2,3-dioxygenase 1 (IDO1) for ubiquitination and degradation by recruiting IDO1 to the CRBN E3 ligase, thereby facilitating its entry into the ubiquitin-proteasome system (UPS) with a DC50 of 2.84 µM. This compound also moderately enhances the tumor-killing efficacy of HER2 CAR-T cells[1].

Produkteigenschaften

• Molekulargewicht: 966.816
• CAS Nummer: [2488851-89-2]
• Formel: C40H53BrFN9O13
• Target-Kategorie: Indoleamine 2,3-Dioxygenase (IDO)|||IDO|||PROTACs

Bilder

T37329