C6 D-threo Ceramide (d18:1/6:0), CAS [[189894-79-9]]
Artikelnummer:
TGM-T37565
Hersteller Artikelnummer:
T37565
Alternativnummer:
TGM-T37565-1MG
Hersteller:
TargetMol
Kategorie:
Biochemikalien
Alternative Synonym:
C6 D-threo Ceramide (d18:1/6:0)
C6 D-threo Ceramide is a bioactive sphingolipid and cell-permeable analog of naturally occurring ceramides., C6 D-threo Ceramide is cytotoxic to U937 cells in vitro (IC50 = 18 µM). It is metabolically inactive and, unlike C6 L-erythro ceramide , C6 D-threo ceramide cannot be converted to C6 glucosylceramide by ceramide glucosyltransferase. C6 D-threo Ceramide promotes survival of isolated rat spinal neurons when used at concentrations up to 2.5 µM but induces cell death at concentrations greater than 5 µM. It enhances IL-4 production induced by phorbol 12-myristate 13-acetate in EL4 T cells when used at a concentration of 10 µM.
Molekulargewicht:
397.63
CAS Nummer:
[189894-79-9]
Formel:
C24H47NO3
Target-Kategorie:
Liposome|||Interleukin|||Others
T37565
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