C6 D-threo Ceramide (d18:1/6:0), CAS [[189894-79-9]]

Catalog Number: TGM-T37565
Article Name: C6 D-threo Ceramide (d18:1/6:0), CAS [[189894-79-9]]
Biozol Catalog Number: TGM-T37565
Supplier Catalog Number: T37565
Alternative Catalog Number: TGM-T37565-1MG
Manufacturer: TargetMol
Category: Biochemikalien
Alternative Names: C6 D-threo Ceramide (d18:1/6:0)
C6 D-threo Ceramide is a bioactive sphingolipid and cell-permeable analog of naturally occurring ceramides., C6 D-threo Ceramide is cytotoxic to U937 cells in vitro (IC50 = 18 µM). It is metabolically inactive and, unlike C6 L-erythro ceramide , C6 D-threo ceramide cannot be converted to C6 glucosylceramide by ceramide glucosyltransferase. C6 D-threo Ceramide promotes survival of isolated rat spinal neurons when used at concentrations up to 2.5 µM but induces cell death at concentrations greater than 5 µM. It enhances IL-4 production induced by phorbol 12-myristate 13-acetate in EL4 T cells when used at a concentration of 10 µM.
Molecular Weight: 397.63
CAS Number: [189894-79-9]
Formula: C24H47NO3
Target: Liposome|||Interleukin|||Others
T37565