StA-IFN-1, CAS [[300839-31-0]]

Artikelnummer: TGM-T38158
Artikelname: StA-IFN-1, CAS [[300839-31-0]]
Artikelnummer: TGM-T38158
Hersteller Artikelnummer: T38158
Alternativnummer: TGM-T38158-1MG, TGM-T38158-5MG, TGM-T38158-10MG
Hersteller: TargetMol
Kategorie: Biochemikalien
StA-IFN-1 is an inhibitor of the interferon (IFN) induction pathway with an IC50 value of 4.1 µM in a GFP reporter assay for IFN induction similar to TPCA-1 , which specifically inhibits the IKKbeta component of the IFN induction pathway. It does not show inhibitory activity in a GFP reporter assay for IFN signaling in which ruxolitinib , which is specific for the IFN signaling component JAK1, is active. StA-IFN-1 reduces the levels of IFN-beta, but not ISG MxA, mRNA, suggesting that it is selective for the IFN induction pathway and not the IFN signaling pathway.
Molekulargewicht: 255.27
CAS Nummer: [300839-31-0]
Formel: C14H13N3O2
Target-Kategorie: Others|||IFNAR
T38158