1-beta-D-Glucosylsphingadienine (d18:2 (4E,8E)), CAS [[114200-59-8]]
Artikelnummer:
TGM-T38213
Hersteller Artikelnummer:
T38213
Alternativnummer:
TGM-T38213-1MG
Hersteller:
TargetMol
Kategorie:
Biochemikalien
Alternative Synonym:
1-beta-D-Glucosylsphingadienine (d18:2 (4E,8E))
1-beta-D-Glucosylsphingadienine is a glucosylsphingosine, which are deacetylated lysolipid derivatives of glucosylcerebrosides . They are formed when sphingosines undergo glucosidation by UDP-glucose. Glucosylsphingosines completely reduce neurite outgrowth and induce death of LA-N-2 cells at concentrations of 10 and 50 µM, respectively. They also decrease the activity of glucocerebrosidase in LA-N-2 cells in a dose-dependent manner. Glucosylsphingosine levels are elevated in patients with Gauchers disease, both in the spleen (in types 1, 2, and 3) and brain (type 2 and 3), thus, glucosylsphingosine has been used as a key biomarker of the disease. This product contains 1-beta-D-glucosylsphingadienine isolated from plants.
Molekulargewicht:
459.624
CAS Nummer:
[114200-59-8]
Formel:
C24H45NO7
Target-Kategorie:
Drug Metabolite|||Others
T38213
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