1-beta-D-Glucosylsphingadienine (d18:2 (4E,8E)), CAS [[114200-59-8]]

Product Overview

• Article Name: 1-beta-D-Glucosylsphingadienine (d18:2 (4E,8E)), CAS [[114200-59-8]]
• Biozol Catalog Number: TGM-T38213
• Supplier Catalog Number: T38213
• Alternative Catalog Number: TGM-T38213-1MG
• Manufacturer: TargetMol
• Category: Biochemikalien
• Alternative Names: 1-beta-D-Glucosylsphingadienine (d18:2 (4E,8E))

Product Description

1-beta-D-Glucosylsphingadienine is a glucosylsphingosine, which are deacetylated lysolipid derivatives of glucosylcerebrosides . They are formed when sphingosines undergo glucosidation by UDP-glucose. Glucosylsphingosines completely reduce neurite outgrowth and induce death of LA-N-2 cells at concentrations of 10 and 50 µM, respectively. They also decrease the activity of glucocerebrosidase in LA-N-2 cells in a dose-dependent manner. Glucosylsphingosine levels are elevated in patients with Gauchers disease, both in the spleen (in types 1, 2, and 3) and brain (type 2 and 3), thus, glucosylsphingosine has been used as a key biomarker of the disease. This product contains 1-beta-D-glucosylsphingadienine isolated from plants.

Product Properties

• Molecular Weight: 459.624
• CAS Number: [114200-59-8]
• Formula: C24H45NO7
• Target: Drug Metabolite|||Others

Images

T38213