NSC 80467 is a selective DNA-damaging agent that functions through survivin inhibition. NSC 80467 preferentially disrupts DNA synthesis, thereby inducing two hallmark DNA-damage markers, gammaH2AX and pKAP1. NSC 80467 enables mechanistic investigation in to DNA replication stress and apoptosis-associated signaling pathways and serves as a biochemical tool for evaluating survivin-dependent cellular processes in oncology research.
Molekulargewicht:
512.35
Reinheit:
99.25%
CAS Nummer:
[101982-51-8]
Formel:
C24H22BrN3O5
Target-Kategorie:
Survivin
T38414
T38414
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten