LXE408 fumarate is an orally active, non-competitive and kinetoplastid-selective proteasome inhibitor. LXE408 fumarate has an IC50 of 0.04 µM for L. donovani proteasome and an EC50 of 0.04 µM for L. donovani. LXE408 fumarate has a low propensity to cross the blood brain barrier. LXE408 fumarate has the potential for visceral leishmaniasis (VL) research.
Molekulargewicht:
559.51
Reinheit:
98.10%
Formel:
C27H22FN7O6
Target-Kategorie:
Proteasome
T39214L
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten