LXE408 fumarate is an orally active, non-competitive and kinetoplastid-selective proteasome inhibitor. LXE408 fumarate has an IC50 of 0.04 µM for L. donovani proteasome and an EC50 of 0.04 µM for L. donovani. LXE408 fumarate has a low propensity to cross the blood brain barrier. LXE408 fumarate has the potential for visceral leishmaniasis (VL) research.
Molecular Weight:
559.51
Purity:
98.10%
Formula:
C27H22FN7O6
Target:
Proteasome
T39214L
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