AG126, CAS [[118409-62-4]]

Produktübersicht

• Artikelname: AG126, CAS [[118409-62-4]]
• Artikelnummer: TGM-T4092
• Hersteller Artikelnummer: T4092
• Alternativnummer: TGM-T4092-1MLX10MM(INDMSO),TGM-T4092-5MG,TGM-T4092-10MG,TGM-T4092-25MG,TGM-T4092-50MG,TGM-T4092-100MG,TGM-T4092-200MG
• Hersteller: TargetMol
• Kategorie: Biochemikalien
• Alternative Synonym: Tyrphostin AG126 , AG 126

Produktbeschreibung

AG126 (Tyrphostin AG126) selectively inhibits the phosphorylation of ERK1 (p44) and ERK2 (p42) at 25-50 µM. It blocks the production of TNF-alpha in vitro2 and in vivo, attenuating signaling through NF-kappaB, the induced expression of COX-2 and iNOS, and the inflammatory response in diverse animal models. AG-126 weakly inhibits epidermal GFRK (IC50: 450 µM) and platelet-derived GFRK (IC50 > 100 µM).

Produkteigenschaften

• Molekulargewicht: 215.16
• Reinheit: 0.9872
• CAS Nummer: [118409-62-4]
• Formel: C10H5N3O3
• Target-Kategorie: ERK|||COX

Bilder

T4092