Poseltinib, CAS [[1353552-97-2]]

Produktübersicht

• Artikelname: Poseltinib, CAS [[1353552-97-2]]
• Artikelnummer: TGM-T4413
• Hersteller Artikelnummer: T4413
• Alternativnummer: TGM-T4413-1MLX10MM(INDMSO),TGM-T4413-2MG,TGM-T4413-5MG,TGM-T4413-10MG,TGM-T4413-25MG,TGM-T4413-50MG,TGM-T4413-100MG,TGM-T4413-200MG
• Hersteller: TargetMol
• Kategorie: Biochemikalien
• Alternative Synonym: HM71224 , HM 71224 , LY 3337641 , LY3337641

Produktbeschreibung

Poseltinib is an orally active, selective, and irreversible inhibitor of Brutons tyrosine kinase (BTK), with an IC50 value of 1.95 nM. Poseltinib demonstrates 0.3-, 2.3-, and 2.4-fold higher selectivity for BTK over BMX, TEC, and TXK, respectively. Poseltinib covalently binds to cysteine 481 in BTKs active site, thereby inhibiting BCR-, FcR-, and TLR-mediated signaling pathways.

Produkteigenschaften

• Molekulargewicht: 470.52
• CAS Nummer: [1353552-97-2]
• Formel: C26H26N6O3
• Target-Kategorie: TLR|||BTK|||Others

Bilder

T4413

T4413