Avapritinib, CAS [[1703793-34-3]]

Produktübersicht

• Artikelname: Avapritinib, CAS [[1703793-34-3]]
• Artikelnummer: TGM-T5109
• Hersteller Artikelnummer: T5109
• Alternativnummer: TGM-T5109-1MLX10MM(INDMSO),TGM-T5109-1MG,TGM-T5109-5MG,TGM-T5109-10MG,TGM-T5109-25MG,TGM-T5109-50MG,TGM-T5109-100MG,TGM-T5109-200MG
• Hersteller: TargetMol
• Kategorie: Biochemikalien
• Alternative Synonym: BLU-285

Produktbeschreibung

Avapritinib (BLU-285) is a selective, highly potent, and orally active inhibitor of KIT and PDGFRA activation loop mutant kinases, targeting KIT D816V (IC50:0.27 nM) and PDGFRA D842V (IC50:0.24 nM), and attenuates the transport functions of ABCB1 and ABCG2. It binds to the active conformation of the kinases and exhibits antitumor activity.

Produkteigenschaften

• Molekulargewicht: 498.56
• Reinheit: 99.70%
• CAS Nummer: [1703793-34-3]
• Formel: C26H27FN10
• Target-Kategorie: PDGFR|||c-Kit

Bilder

T5109