PBRM1-BD2-IN-5, CAS [[2819989-61-0]]

Produktübersicht

• Artikelname: PBRM1-BD2-IN-5, CAS [[2819989-61-0]]
• Artikelnummer: TGM-T60159
• Hersteller Artikelnummer: T60159
• Alternativnummer: TGM-T60159-1MLX10MM(INDMSO),TGM-T60159-1MG,TGM-T60159-5MG,TGM-T60159-10MG,TGM-T60159-25MG,TGM-T60159-50MG,TGM-T60159-100MG,TGM-T60159-200MG
• Hersteller: TargetMol
• Kategorie: Biochemikalien

Produktbeschreibung

PBRM1-BD2-IN-5 is a potent inhibitor of the PBRM1 Bromodomain, with dissociation constant (Kd) values of 1.5 µM and 3.9 µM for PBRM1-BD2 and PBRM1-BD5 respectively, and an inhibitory concentration 50 (IC50) value of 0.26 µM for PBRM1-BD2. This compound effectively diminishes the interaction between full-length PBRM1 and acetylated histone peptide within the PBAF complex in cell lysates, making it a promising candidate for anticancer research.

Produkteigenschaften

• Molekulargewicht: 272.73
• Reinheit: 99.51%
• CAS Nummer: [2819989-61-0]
• Formel: C15H13ClN2O
• Target-Kategorie: Epigenetic Reader Domain

Bilder

T60159