PBRM1-BD2-IN-5, CAS [[2819989-61-0]]

Product Overview

• Article Name: PBRM1-BD2-IN-5, CAS [[2819989-61-0]]
• Biozol Catalog Number: TGM-T60159
• Supplier Catalog Number: T60159
• Alternative Catalog Number: TGM-T60159-1MLX10MM(INDMSO),TGM-T60159-1MG,TGM-T60159-5MG,TGM-T60159-10MG,TGM-T60159-25MG,TGM-T60159-50MG,TGM-T60159-100MG,TGM-T60159-200MG
• Manufacturer: TargetMol
• Category: Biochemikalien

Product Description

PBRM1-BD2-IN-5 is a potent inhibitor of the PBRM1 Bromodomain, with dissociation constant (Kd) values of 1.5 µM and 3.9 µM for PBRM1-BD2 and PBRM1-BD5 respectively, and an inhibitory concentration 50 (IC50) value of 0.26 µM for PBRM1-BD2. This compound effectively diminishes the interaction between full-length PBRM1 and acetylated histone peptide within the PBAF complex in cell lysates, making it a promising candidate for anticancer research.

Product Properties

• Molecular Weight: 272.73
• Purity: 99.51%
• CAS Number: [2819989-61-0]
• Formula: C15H13ClN2O
• Target: Epigenetic Reader Domain

Images

T60159