(S)-Bromoenol lactone is a chiral, mechanism-based irreversible inhibitor targeting calcium-independent phospholipase A2(iPLA2). Compared with its enantiomer (R)-BEL, (S)-Bromoenol lactone has higher selectivity for iPLA2gamma(Group VIB), and it is often used in combination with (R)-BEL to distinguish the functions of different subtypes of iPLA2 in arachidonic acid release and cell signal transduction.
Molekulargewicht:
317.18
CAS Nummer:
[478288-94-7]
Formel:
C16H13BrO2
Target-Kategorie:
Others
T60832
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