CXCR4 antagonist 8 (Compound 3) is a potent inhibitor of CXCR4, exhibiting an IC50 value of 57 nM in antagonism and effectively inhibiting CXCL12-induced cytosolic calcium increase with an IC50 of 0.24 nM. Additionally, Compound 3 is efficacious in inhibiting CXCL12/CXCR4-mediated cell migration [1].
Molekulargewicht:
362.47
CAS Nummer:
[2304750-84-1]
Formel:
C21H26N6
Target-Kategorie:
Others|||CXCR
T61363
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