Ipatasertib, CAS [[1001264-89-6]]

Produktübersicht

• Artikelname: Ipatasertib, CAS [[1001264-89-6]]
• Artikelnummer: TGM-T6252
• Hersteller Artikelnummer: T6252
• Alternativnummer: TGM-T6252-1MLX10MM(INDMSO),TGM-T6252-2MG,TGM-T6252-5MG,TGM-T6252-10MG,TGM-T6252-25MG,TGM-T6252-50MG,TGM-T6252-100MG
• Hersteller: TargetMol
• Kategorie: Biochemikalien
• Alternative Synonym: GDC-0068 , RG7440

Produktbeschreibung

Ipatasertib (GDC-0068) is a selective, ATP-competitive pan-Akt inhibitor that inhibits Akt1 (IC50:5 nM), Akt2 (IC50:18 nM), and Akt3 (IC50:8 nM). Ipatasertib (GDC-0068) can lead to p53-independent PUMA activation by inhibiting Akt, thereby activating FoxO3a and NF-kappaB simultaneously, directly binding to the PUMA promoter, upregulating PUMA transcription and Bax-mediated intrinsic mitochondrial apoptosis.

Produkteigenschaften

• Molekulargewicht: 458
• Reinheit: 98.28%
• CAS Nummer: [1001264-89-6]
• Formel: C24H32ClN5O2
• Target-Kategorie: Akt|||Apoptosis

Bilder

T6252