Ipatasertib, CAS [[1001264-89-6]]

Product Overview

• Article Name: Ipatasertib, CAS [[1001264-89-6]]
• Biozol Catalog Number: TGM-T6252
• Supplier Catalog Number: T6252
• Alternative Catalog Number: TGM-T6252-1MLX10MM(INDMSO),TGM-T6252-2MG,TGM-T6252-5MG,TGM-T6252-10MG,TGM-T6252-25MG,TGM-T6252-50MG,TGM-T6252-100MG
• Manufacturer: TargetMol
• Category: Biochemikalien
• Alternative Names: GDC-0068 , RG7440

Product Description

Ipatasertib (GDC-0068) is a selective, ATP-competitive pan-Akt inhibitor that inhibits Akt1 (IC50:5 nM), Akt2 (IC50:18 nM), and Akt3 (IC50:8 nM). Ipatasertib (GDC-0068) can lead to p53-independent PUMA activation by inhibiting Akt, thereby activating FoxO3a and NF-kappaB simultaneously, directly binding to the PUMA promoter, upregulating PUMA transcription and Bax-mediated intrinsic mitochondrial apoptosis.

Product Properties

• Molecular Weight: 458
• Purity: 98.28%
• CAS Number: [1001264-89-6]
• Formula: C24H32ClN5O2
• Target: Akt|||Apoptosis

Images

T6252